This is Irish comedian Dara O'Briain using a few naughty but well-chosen words to say some things I think are worth saying.
If you don't have six minutes to spare or don't like naughty words, I'll boil it down: "Science knows it doesn't know everything. Otherwise it'd stop." That's your bumpersticker, right there.
I can see it.
P.S.: Just to avoid any confusion and save you the trouble of looking it up yourself, I believe his last joke that ends "You look like Noddy" refers to this fella: